Administrative Supplements


The NIH invites eligible NIH CFARs and NIMH ARCs to submit administrative supplements in support of the Ending the HIV Epidemic in the United States initiative. Eligible CFARs and ARCs must collaborate with partners in the 57 priority areas: community, local, county and state health departments, CBOs, and clinics funded by the CDC, HRSA, SAMHSA, or IHS. These implementation research projects should be developed by a team of CFAR/ARC investigators, community partners, implementing collaborators, and people with lived experience to support the local ending the HIV epidemic plans.

Each CFAR may submit one application to the NIH for each of the research topics listed below. Applicants must submit a Letter of Intent (LOI) to SD CFAR by Friday, February 11 at 12:00 pm PT for consideration. A total of up to five (5) applications will be submitted to NIAID through the SD CFAR Administrative Core. Notifications of selected LOIs will be sent by February 16th. 

Research Topics

1. Planning projects to support participatory data science research efforts toward Ending the HIV Epidemic in the United States - $200,000 Direct Costs for up to 1 year

2. Equity-focused approaches to reduce HIV-related health disparities - $200,000 Direct Costs for up to 1 year*

3. Strategic alliances across jurisdictions to reach EHE goals through implementation research - $250,000 Direct Costs for up to 1 year

4. Applying behavioral economic approaches to design implementation strategies for HIV testing, prevention, and care - $200,000 Direct Costs for up to 1 year

5. Implementation Strategies to Facilitating a Status Neutral Approach to HIV Prevention and Treatment - $200,000 Direct Costs for up to 1 year

*Important Note: See LOI guidance document for details about this project period.



2022 Application Timeline


LOIs due to SD CFAR Friday, February 11 by 12:00 pm PT
Applicants notified Wednesday, February 16
Applications due for internal review** Wednesday, March 9
Internal review panels/mock study sections** Wednesday, March 16 - Friday, March 18
Final applications due to SD CFAR Wednesday, March 23 by 12:00 pm PT
SD CFAR submits applications for UCSD institutional review Monday, March 28
Applications due at NIH Monday, April 4


**Internal review participation is optional, however strongly encouraged


Letter of Intent Guidelines


Click here to download a pdf of Letter of Intent Guidelines



Preferred length: Two pages. Please be as succinct as possible. References may be placed on a separate page.


Preferred format: Use at least half-inch margins on all sides, and 11-point type or larger in the body of your letter. Headers and footers may have smaller type if it is legible. No tables or figures, please.

Basic information:

  1. Supplement PI name, academic title, email address, and SD CFAR institution
  2. List of other proposed Senior/Key Personnel
  3. EHE Topic
  4. Project Title
  5. Primary Pillar and Other pillars
  6. EHE geographic priority area(s) (name of the county, territory, or state)
  7. Implementing Partner (organization name and collaborator name)
  8. Community Partner (organization name and collaborator name)
  9. Project/Performance Site location(s)

Preferred content:

State and define the following:

  • Problem/research question: What do you wish to study and why? Provide background information and list previous research in this area if possible.
  • Objectives: What will the proposed research accomplish?
  • Specific Aims: State each Aim using active verbs, then define how you propose to achieve it. Please also state your hypothesis/hypotheses for each Aim.
    • Indicate how the proposed activities outlined in the supplement announcement are expected to support your Specific Aims.
  • Implementation Science Framework: Provide a brief description of the implementation science framework or model you plan to utilize.
  • Inter-CFAR Synergy: Include a statement of how you plan to utilize existing SD CFAR resources (including Cores and the EHE SWG) and/or develop unique expertise, technology, and resources at SD CFAR institutions.
  • Human or animal subjects’ involvement: Describe any research to be done in enrolled participants. If using stored specimens, how were they obtained and where are they stored? Do you need or have IRB or IACUC approval? If your study does not involve human or animal subjects, skip to Next Steps.
  • Next steps: How will you use the data resulting from this proposed research?


Please refer to deadlines above and note there is a tight turnaround time to submit final applications. SD CFAR will be organizing optional, internal reviews for the final applicants. 



Background on NIH Administrative Supplements

NIH occasionally announces opportunities for administrative supplements. These are grants in specific aspects of HIV research that are offered to all CFAR sites for periods of one or more years. They are considered supplemental funding to the sites' CFAR grant.

When we are informed of a new administrative supplement, we announce the opportunity and application instructions by email to our members.

We hope you will apply for one of these supplements. Please remember to acknowledge the San Diego CFAR in any publication that results from one of our grant opportunities.

At a Glance