Clinical Data, Specimen Repository and Investigator Access

The CI Core provides access to rich clinical data and biospecimen resources that support HIV-related research across diverse populations. These resources are not limited to the Owen Clinic; rather, they are part of a national, well?characterized research network that enables investigators to assess feasibility and pursue analyses efficiently.

Clinical Data and Biospecimen Repository

The University of California San Diego CFAR participates in the CFAR Network of Integrated Clinical Systems (CNICS), a multi-site clinical cohort that integrates:

• Longitudinal clinical data derived from routine HIV care
• Demographic, treatment, and outcomes data
• Linked biospecimens collected using standardized protocols

Information about available datasets, specimen types, and participating sites is maintained centrally through CNICS.

Comprehensive and up-to-date details are available via the CNICS website.

This site provides investigators with:

• Detailed descriptions of available specimen types (e.g., plasma, serum, PBMCs)
• Information on populations represented (e.g., age, sex, race/ethnicity, transmission risk, comorbidities)
• Data elements and collection time points
• Governance and access procedures

How Investigators Determine Sample Availability

Investigators—including early stage and those new to SD CFAR—do not need prior engagement to assess feasibility. Sample and data availability can be determined by:

1. Reviewing CNICS documentation (linked above), which outlines specimen inventories and cohort characteristics.
2. Consulting searchable resources provided through CNICS (e.g., structured data dictionaries and feasibility tools).
3. Engaging directly with the CI Core (submit a service request here!) to discuss specific populations or scientific questions.

We recognize that navigating large repositories can feel like a barrier, particularly for emerging investigators. To reduce this, our CI Core team can help investigators identify whether samples relevant to a specific population or research question are available and guide next steps.

How to Request Access

Access to CNICS data or biospecimens follows an established review process coordinated through the CI Core and CNICS governance. The CI Core provides hands-on support with:

• Feasibility discussions
• Determining appropriate datasets or specimen types
• Navigating submission and approval processes
• Connecting investigators with methodologic or analytic expertise

Contact Us

We strongly encourage investigators to reach out early with questions—particularly if you are unsure whether samples or data exist for your population of interest. Please submit a service request here.

Our goal is to make these resources accessible and to actively support investigator engagement, from project conception through implementation.

Cite CNICS

Support CNICS by citing them in your publications, abstracts and grants.