Welcome to the CFAR Genomics Core
If work performed for you at the CFAR Genomics Core results in publication please acknowledge us with the following statement so that we may continue to bring you excellent service: |
"This work was performed with the support of the Genomics Core at the UCSD Center for AIDS Research (AI36214) and the San Diego Veterans Medical Research Foundation."
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The primary objectives of the Genomics Core are to provide:
- Validation of gene expression data using real-time quantitative RT-PCR (qRT-PCR) technology (TaqMan, Amplifluor and SYBRGreen).
- Bioinformatics analysis of microarray gene expression data.
- Phylogenetic analysis of virus sequence data.
(For a full list of our services please click on "SERVICES" in the menu bar.)
To use services at the Genomics Core please visit our "Request Services" page.
Mission Statement:
The mission of the Genomics Core laboratory is to provide expertise in the arena of genomics and sequence analysis, and to develop new services in these fields at the request of core users.
Genomics Core Overview:
Recent advances in genome sequencing and high throughput technology to analyze gene expression has placed biology at the forefront of modern science. The Genomics Core is able to provide services, reagents and expertise to perform a number of assays ranging from small-scale to large-scale analysis of gene expression, microRNA detection, SNP detection, and Taqman Low Density Arrays. Projects pertaining to HIV research will be given additional assistance. The core is equiped with an ABI Prism 7700 Sequence Detection System and a 7900HT Fast Real Time PCR System for qRT-PCR analysis, and a Sun Microsystems Sunfire 880 dual processor (UltraSPARC) machine for bioinformatic analyses. The core staff are highly trained and skilled in areas of RNA isolation, purification and quantification, primer design, and gene expression and phylogenetic analysis.
The Genomics Core is sponsored by the UCSD Center for AIDS Research (CFAR) and the Veterans Medical Research Foundation (VMRF). We are assisted by the School of Medicine, the San Diego Supercomputer Center (SDSC) and the School of Bioengineering in developing the necessary tools to meet any bioinformatic challenges. For your microarray needs please refer to the GeneChip Microarray Core (Affymetrix GeneChips) or the Biomedical Genomics Microarray Laboratory (Amersham Codelink BioChips, Agilent Olignucleotide Microarrays and ABI Microarrays). For a source of biological reagents and supplies visit the UCSD Core Bio Services. The services provided by these cores coupled with our qRT-PCR validation and bioinformatic expertise provides researchers with the ability to harness the capabilities of the very latest technologies in genomics research.
The Genomics Core aims to provide both the academic and industrial communities with the relevant genomics tools to take their research in new directions.